PROVENGE Is Now FDA Approved

PROVENGE is the first FDA-approved autologous cellular immunotherapy for the treatment of asymptomatic or minimally symptomatic metastatic castrate resistant (hormone refractory) prostate cancer. Read the New England Journal of Medicine article.

What is PROVENGE?

PROVENGE, the first FDA-approved autologous cellular immunotherapy, is a breakthrough treatment that uses a patient's own antigen-presenting cells to stimulate the body's immune system against prostate cancer. Learn more about how PROVENGE is designed to work.

The information on this site will be updated as new information and resources become available. Watch the PROVENGE Journey video to learn more about how PROVENGE is made.

For information such as ordering, scheduling, tracking, and general coverage and reimbursement questions, contact a Dendreon ON Call specialist at (877) 336-3736.

Please visit Dendreon.com to learn more about our mission to target cancer and transform lives through the discovery, development, and commercialization of novel therapeutics.

INDICATION AND IMPORTANT SAFETY INFORMATION

PROVENGE® (sipuleucel-T) is approved by the FDA as an autologous cellular immunotherapy for the treatment of asymptomatic or minimally symptomatic metastatic castrate resistant (hormone refractory) prostate cancer.

PROVENGE is made from your own immune cells. Your cells will be collected at a cell collection center approximately 3 days before each scheduled infusion of PROVENGE. There can be risks associated with the cell collection process, which you should discuss with your doctor before deciding to begin treatment with PROVENGE.

PROVENGE can cause serious reactions. In controlled clinical trials for the treatment of prostate cancer, serious reactions reported in patients in the PROVENGE group include reactions resulting from the infusion of the drug, which occurred within 1 day of infusion, and strokes. Severe infusion reactions included chills, fever, fatigue, weakness, breathing problems (shortness of breath, decreased oxygen level, and wheezing), dizziness, headache, high blood pressure, muscle ache, nausea, and vomiting. Tell your doctor right away if you have breathing problems, chest pains, racing heart or irregular heartbeats, dizziness, nausea, or vomiting after getting PROVENGE because any of these may be signs of heart or lung problems.

The most common side effects reported with PROVENGE are chills, fatigue, fever, back pain, nausea, joint ache, and headache. These are not all the possible side effects of PROVENGE treatment. For more information, talk with your doctor.

Tell your doctor about all your medical problems including heart problems, lung problems or a history of stroke.

Tell your doctor right away if you get a fever over 100°F, or redness at the cell collection or infusion sites, because any of these may be signs of infection.

Tell your doctor about all the medicines you take, including prescription and nonprescription drugs, vitamins, and dietary supplements.

Tell your doctor about any side effect that concerns you or does not go away.

For more information on PROVENGE, please see the Full Prescribing Information or call Dendreon at 1-877-336-3736.